Domperidone

The package insert describes relief of fullness, nausea, upper-belly bloating and belching after meals, sometimes with discomfort and heartburn.

It is also used for nausea and vomiting lasting less than 48 hours.

• Post-meal fullness and bloating
• Nausea and vomiting under 48 hours
• Belching and heartburn-type discomfort

The label says it is a dopamine antagonist that works through a stomach-moving effect and by blocking dopamine receptors in the brain area that triggers vomiting.

This page covers the Indian package insert for domperidone tablets taken by mouth, with the dosing the label gives for adults and, where the label says so, children.

This is label-level information, not personal advice. Indian pack labels may differ, and your prescriber's instruction always comes first.

The label says the tablet is dispersed in a teaspoon of water before use. For post-meal discomfort, adults and children aged 16 and over take up to 10 mg three times a day and at night, for no more than 2 weeks.

For nausea and vomiting, the same dose is described for no more than 48 hours. Use in children under 16 is not recommended.

• Up to 10 mg three times daily and at night
• Discomfort: maximum 2 weeks
• Nausea or vomiting: maximum 48 hours
• Not recommended under 16 years

The label says it must not be used with allergy, prolactin-releasing pituitary tumour, liver or kidney impairment, or when stimulating the gut could be harmful, such as bleeding, blockage or perforation.

Use is not recommended during breastfeeding or in infants, and not with potent CYP3A4 inhibitors such as ketoconazole due to QT prolongation.

• Pituitary prolactinoma
• Liver or kidney impairment
• Gut bleeding, blockage or perforation
• Breastfeeding and infants: not recommended
• QT prolongation risk

• Ketoconazole
• Erythromycin
• Potent CYP3A4 inhibitors
• The label names ketoconazole and erythromycin as interacting when taken together.
• Potent CYP3A4 inhibitors are not recommended because of QT prolongation.

No match in this label text. Ask your pharmacist about any medicine you take.

The label text we reviewed gives no storage temperature for this product.

Follow the storage line on your own pack, and keep medicines out of the reach of children.

In the Drugs Rules schedules we checked, domperidone is listed under Schedule H (serial and rule: Schedule H, serial 161 (rules 65 and 97)). Schedule H medicines are sold only on a registered doctor's prescription.

Domperidone is on the National List of Essential Medicines 2022. Listed forms include: Tablet 10 mg (page 94); Oral Liquid 1 mg/mL (page 94).

NPPA lists ceiling prices for scheduled domperidone formulations. The table shows the rows we found. Check NPPA directly for the current list.

The Jan Aushadhi (PMBJP) list we checked has 3 product rows that mention domperidone. We did not capture prices for them.

The banned fixed-dose combination list we checked has 10 entries that mention domperidone. This does not mean the single medicine is banned. Use our checker for a specific combination.

NPPA ceiling prices set the most a seller can charge per unit for the listed formulations, before local taxes. They are ceilings, not the price you will always pay.

Jan Aushadhi lists domperidone products including Domperidone Tablets IP 10 mg 10 mg; Domperidone Suspension IP 5mg per 5ml 5mg per 5ml; Domperidone 10mg and Paracetamol 325mg Tablets 10mg. We have not shown a price for them. Check the pack and the seller for the actual price.