Oxybutynin Chloride

The label describes oxybutynin chloride for relief of symptoms of bladder instability associated with voiding, in people with uninhibited or reflex neurogenic bladder.

The symptoms named include urgency, frequency, urinary leakage, urge incontinence and painful urination.

• Urgency and frequency
• Urinary leakage and urge incontinence
• Painful urination
• In neurogenic bladder

The label says oxybutynin relaxes bladder smooth muscle. It has a direct antispasmodic effect and blocks the muscarinic action of acetylcholine on smooth muscle.

This page covers the US label for oxybutynin chloride tablets taken by mouth, with the dosing the label gives for adults and, where the label says so, children.

This is label-level information, not personal advice. Indian pack labels may differ, and your prescriber's instruction always comes first.

For adults, the label describes the usual dose as one 5 mg tablet two to three times a day, with a maximum of one 5 mg tablet four times a day.

For frail elderly people, a lower starting dose of 2.5 mg two or three times a day is described.

For children over 5 years, the usual dose is one 5 mg tablet twice a day, with a maximum of one 5 mg tablet three times a day.

• Adults: 5 mg two to three times daily
• Maximum 5 mg four times daily
• Frail elderly: 2.5 mg two or three times daily
• Children over 5: 5 mg twice daily

The label says oxybutynin is contraindicated in urinary retention, gastric retention and other severe slow gut conditions, uncontrolled narrow-angle glaucoma, and known allergy to it.

The label advises caution in the frail elderly, in liver or kidney impairment, and in dementia treated with cholinesterase inhibitors, Parkinson's disease, myasthenia gravis, and bladder outflow obstruction.

The label says its safety in pregnant women has not been established. It is not known whether it passes into breast milk, so caution is advised.

• Urinary or gastric retention
• Uncontrolled narrow-angle glaucoma
• Angioedema can be life-threatening
• Caution in frail elderly, dementia, Parkinson's disease
• Caution in liver or kidney impairment
• Pregnancy and breastfeeding: caution

• Other anticholinergic drugs
• Ketoconazole, itraconazole, miconazole
• Erythromycin and clarithromycin
• Metoclopramide
• The label says other anticholinergic drugs or drugs causing dry mouth, constipation or drowsiness may increase these effects.
• Ketoconazole raised oxybutynin levels about 3 to 4 times.
• Other CYP3A4 inhibitors such as itraconazole, miconazole, erythromycin and clarithromycin may also change levels, so caution is advised.
• It may also antagonize prokinetic agents such as metoclopramide.

No match in this label text. Ask your pharmacist about any medicine you take.

The label gives a storage range of 20 to 25 degrees C.

The label also says to keep the container tightly closed.

Follow the storage line on your own pack, and keep medicines out of the reach of children.

In the Drugs Rules schedules we checked, oxybutynin chloride is listed under Schedule H (serial and rule: Schedule H, serial 378 (rules 65 and 97)). Schedule H medicines are sold only on a registered doctor's prescription.

We did not find oxybutynin chloride on the National List of Essential Medicines 2022 in the list we checked.

The Jan Aushadhi (PMBJP) list we checked has 1 product row that mention oxybutynin chloride. We did not capture prices for them.

Jan Aushadhi lists oxybutynin chloride products including Oxybutynin Chloride 2.5mg Tablets 2.5mg. We have not shown a price for them. Check the pack and the seller for the actual price.