Sumatriptan

The label describes sumatriptan tablets for the acute treatment of migraine attacks, with or without aura, in adults.

It is not meant to prevent migraine or to treat hemiplegic or basilar migraine. Safety and effectiveness for cluster headache have not been established.

• Acute migraine attacks, with or without aura
• Not for preventing migraine
• Not for hemiplegic or basilar migraine

Sumatriptan acts on a blood vessel serotonin receptor, probably the 5-HT1D type. The label says it has only weak effects on other receptors.

This page covers the US label for sumatriptan tablets taken by mouth, with the dosing the label gives for adults and, where the label says so, children.

This is label-level information, not personal advice. Indian pack labels may differ, and your prescriber's instruction always comes first.

For adults, the label describes single doses of 25, 50 or 100 mg. Doses of 50 and 100 mg may work better than 25 mg, and 100 mg did not show more effect than 50 mg.

If the headache returns or only partly responds, a dose may be repeated after 2 hours, up to 200 mg a day.

With liver disease, the single dose should generally not exceed 50 mg. The label says safety of treating more than 4 headaches in 30 days has not been established.

• Single doses of 25, 50 or 100 mg
• Repeat after 2 hours if needed
• Maximum 200 mg a day
• Lower single dose with liver disease

It should not be given to people with a history, symptoms or signs of ischemic heart, brain or peripheral blood vessel disease, or other significant cardiovascular disease.

It should only be used when migraine has been clearly diagnosed. People with heart risk factors such as high blood pressure, smoking, diabetes or age over 40 in men may need a heart check first.

Pregnancy Category C: use only if the benefit justifies the risk to the baby.

• Not with heart, stroke or vascular disease
• Heart check may be needed for people with risk factors
• Use only with a clear migraine diagnosis
• Lower dose with liver disease
• MAO-A inhibitors are contraindicated

• MAO-A inhibitors (contraindicated)
• SSRIs and similar antidepressants
• Other serotonin-affecting medicines
• MAO-A inhibitors increase sumatriptan levels, and their combined use is contraindicated.
• The label also discusses selective serotonin reuptake inhibitors, which can rarely cause weakness or other serotonin-related effects.
• Alcohol taken before the dose did not change sumatriptan levels in a study.

No match in this label text. Ask your pharmacist about any medicine you take.

The label gives a storage range of 20 to 25 degrees C.

The label also says to keep the container tightly closed.

Follow the storage line on your own pack, and keep medicines out of the reach of children.

In the Drugs Rules schedules we checked, sumatriptan is listed under Schedule H (serial and rule: Schedule H, serial 477 (rules 65 and 97)). Schedule H medicines are sold only on a registered doctor's prescription.

Sumatriptan is on the National List of Essential Medicines 2022. Listed forms include: Tablet 25 mg (page 67); Tablet 50 mg (page 67).

NPPA lists ceiling prices for scheduled sumatriptan formulations. The table shows the rows we found. Check NPPA directly for the current list.

The Jan Aushadhi (PMBJP) list we checked has 2 product rows that mention sumatriptan. We did not capture prices for them.

NPPA ceiling prices set the most a seller can charge per unit for the listed formulations, before local taxes. They are ceilings, not the price you will always pay.

Jan Aushadhi lists sumatriptan products including Sumatriptan 85mg and Naproxen 500mg Tablets 85mg; Sumatriptan 50 Mg Tablets 50 Mg. We have not shown a price for them. Check the pack and the seller for the actual price.