Tobramycin

The label describes this product for the management of cystic fibrosis patients with Pseudomonas aeruginosa.

It says safety and efficacy are not demonstrated under age six, with very low or high lung function, or with Burkholderia cepacia.

• Cystic fibrosis with Pseudomonas aeruginosa
• Not established under age 6

Tobramycin is an aminoglycoside antibacterial. It disrupts bacterial protein making, which damages the cell envelope and kills the bacteria.

It is active against Gram-negative bacteria including Pseudomonas aeruginosa.

This page covers the US label for tobramycin capsules taken by mouth, with the dosing the label gives for adults and, where the label says so, children.

This is label-level information, not personal advice. Indian pack labels may differ, and your prescriber's instruction always comes first.

The label says the capsules are for oral inhalation only, using the Podhaler device, and must not be swallowed. For adults and children six and older, a set number of capsules is inhaled twice daily for 28 days, then stopped for 28 days.

Doses should be as close to 12 hours apart as possible and not less than 6 hours apart. Capsules should stay in the blister until immediately before use.

The label says that if other inhaled medicines or chest physiotherapy are used, this product is recommended last.

• Inhale only, never swallow
• Use only with the Podhaler device
• 28 days on, then 28 days off
• Twice daily, about 12 hours apart

The label says it is contraindicated with known hypersensitivity to any aminoglycoside.

Caution is advised with known or suspected hearing, balance, kidney or muscle problems. It can cause bronchospasm and ototoxicity, including in people with certain mitochondrial gene variants.

Aminoglycosides can cause fetal harm, including congenital deafness reported with streptomycin.

• Not for aminoglycoside allergy
• Bronchospasm
• Hearing and balance damage
• Kidney and muscle weakness caution
• Can cause fetal harm

• Other neurotoxic, nephrotoxic or ototoxic drugs
• Furosemide and ethacrynic acid
• Urea and intravenous mannitol
• The label says to avoid use with other drugs that can harm nerves, kidneys or hearing.
• It says it should not be given with ethacrynic acid, furosemide, urea or intravenous mannitol.

No match in this label text. Ask your pharmacist about any medicine you take.

The label gives a storage range of 15 to 30 degrees C.

The label also says to keep it away from moisture.

Follow the storage line on your own pack, and keep medicines out of the reach of children.

We did not find tobramycin in the Drugs Rules 1945 Schedule H, H1, X or G rows we checked, so we cannot state its Indian prescription status from our lists. Ask your pharmacist or doctor.

We did not find tobramycin on the National List of Essential Medicines 2022 in the list we checked.

The Jan Aushadhi (PMBJP) list we checked has 2 product rows that mention tobramycin. We did not capture prices for them.

The banned fixed-dose combination list we checked has 1 entries that mention tobramycin. This does not mean the single medicine is banned. Use our checker for a specific combination.

Jan Aushadhi lists tobramycin products including Tobramycin Eye Drops 0.3%w/v 0.3%w/v; Tobramycin 0.3% w/v and Fluoromethalone 0.1% w/v Opthalmic Solution IP None. We have not shown a price for them. Check the pack and the seller for the actual price.